Among their many innovations, the Sumerians pioneered cuneiform, or wedge-shaped writing on clay tablets, representing numbers up to 60 in a base 10 sequence of increasing stylus strokes.

Duloxetine at 60 mg daily is effective in treating painful diabetic peripheral neuropathy in the short term, with a risk ratio (RR) for ≥ 50% pain reduction at 12 weeks of 1.73 (95% CI 1.44 to 2.08).