§ Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI) - ESPCI ParisTech/CNRS (UMR8231)/PSL* Research University, 10 rue Vauquelin, 75231 CEDEX 05 Paris, France # ...

Abstract: DNA sequence and structure design is very important for DNA nanoapplications. A computer-aided design tool is needed for exploring DNA sequence and structure of interests before experimental ...

Here, we reviewed the recent advances of applying the rational design strategy to engineer enzyme functions including activity and enantioselectivity. Five strategies including multiple sequence ...

Template-based protein design relies on using existing protein structures as starting points to guide the design process - for both sequence and backbone redesign. Since protein structure determines ...

College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China Centralab, Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine, Suzhou 215028, China ...

These innovations reflect the quality and depth of our in vivo data, the power of our AI algorithms for sequence design, and our commitment to helping partners develop exceptional gene therapies ...

Dyno’s platform applies advanced AI models trained on data from high-throughput in vivo measurements in animal models to design AAV capsids that are optimized for delivery efficiency ...

We deepen into Frequency Hopping Sequence (FHS) mechanisms within LR-FHSS, spotlighting the potential of leveraging Wide-Gap sequences. Concurrently, we introduce two novel demodulator allocation ...