Despite being a rookie, Isaac Guerendo made the most of the 2024 NFL ... However, his most productive week was against the Seahawks, where he totaled 99 yards, including a 76-yard longest run ...

And what we've got with Isaac Guerendo is some risk ... Almost no faith in the Seahawks or Steelers in massive matchups 12 NFL head coaching candidates with Bill Belichick going to North Carolina ...

San Francisco 49ers rookie running back Isaac Guerendo saves his career-long rush ... "Thursday Night Football" win over the Seattle Seahawks Kansas City Chiefs' wide receiver Xavier Worthy ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. The rookie was carted off the field, and the team ...

Coach Kyle Shanahan said Guerendo (foot/hamstring) will be limited at Thursday's practice, Cam Inman of The San Jose Mercury News reports. As Shanahan projected Monday, Guerendo is returning to ...

The Fantasy Football Podcast crew all believe Isaac Guerendo is in a great position as the 49ers lead back in Week 16 vs. the Dolphins.

Unfortunately, that didn't prove to be the case. Less than two minutes into the game, San Francisco's third-choice running back Isaac Guerendo suffered a left knee injury after it was twisted at ...

San Francisco 49ers running back Isaac Guerendo is dealing with a hamstring injury and is unlikely to play Sunday at the Miami Dolphins, a source told ESPN's Adam Schefter on Thursday. Guerendo ...

San Francisco 49ers running back Isaac Guerendo's second touchdown of day gets 49ers to 30-point mark vs. Chicago Bears. Watch the highlights from Super Bowl LIX between the Kansas City Chiefs and ...

Rookie Isaac Guerendo went down on the fourth play of the game and his second carry. He suffered knee and ankle injuries and had to be carted off the field. He had gained five yards on two carries.

San Francisco 49ers running backs Christian McCaffrey and Isaac Guerendo had good news on their late-season injuries, and both appear to be on track to be ready for the start of the 2025 season.