49ers third-string running back Isaac Guerendo isn't widely owned in fantasy leagues (yet), but he made that decision on "Thursday Night Football" against the Seahawks. This time, though, it wasn ...

SANTA CLARA, CALIFORNIA - NOVEMBER 17: Isaac Guerendo #31 of the San Francisco 49ers warms up before a game against the Seattle Seahawks at Levi's Stadium on November 17, 2024 in Santa Clara ...

Kittle, Bosa and Williams Questionable for Week 11 vs. Seahawks; Injury Report #SEAvsSF The San Francisco 49ers released their latest injury updates headed into the team's Week 11 matchup vs. the ...

Maybe you're fading McCaffrey and are targeting Guerendo instead. Or maybe it's the middle-to-late rounds and you want a talented running back who's one injury away from a lot of touches. Guerendo ...

Isaac Guerendo (Week 13: 11 snaps, 5 opportunities, 6 routes, 1 target) Notes: Jordan Mason and Christian McCaffrey combined to play on 36 snaps while seeing 23 opportunities. Injuries paved the way ...

The 49ers gave Isaac Guerendo extra credit for this first-quarter catch because it was made on ... That’s his highest total since he had 109 YAC yards in a Week 13 loss to the Seattle Seahawks ...

1. Isaac Guerendo. At RB3 for San Francisco is Guerendo, a rookie drafted in the fourth round back in April. Guerendo played at Wisconsin and Louisville throughout his college career.

Rookie Isaac Guerendo is poised to start for the San Francisco 49ers in today’s clash with the Chicago Bears, ... Against the Seahawks in Week 6, ...

Running back Isaac Guerendo is officially active for the the 49ers' pivotal "Thursday Night Football" game against the Los Angeles Rams despite dealing with a foot injury on a short week.