Study: SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1. Image Credit: Eterysun / Shutterstock.com Although most ...

Research continues to determine BRD7's role in potential treatment Park and colleagues are now back to work. They hope to definitively prove that an alternative insulin signaling pathway exists ...

The insulin-like growth factor 1 (IGF1) signaling pathway is implicated in the development of cancer. High levels of circulating IGF1 and certain genetic polymorphisms of IGF1 and IGFBP3 are ...

The insulin/IGF signaling pathway is a key pathway in the regulation of energy metabolism and cell survival. Therefore, we suspected that SARS-CoV-2 affects this signaling pathway to cause ...

“Obese mice that lack this signaling pathway in endothelial cells show improved insulin sensitivity and glucose tolerance,” they told GEN. Offermanns also shared that they were initially ...

Insulin orchestrates blood glucose levels ... Offermanns and his team made their discovery while studying an unrelated signaling pathway. They observed to their surprise that removing a protein ...

In 2021, a research team led by Prof. Heiko Lickert from Helmholtz Munich discovered the insulin-inhibitory receptor "Inceptor" and its role as a suppressor of the insulin signaling pathway. Now ...

The authors propose that part of the insulin signaling pathway (the branch that activates the protein kinase AKT is inhibited in the fat body of gamergates and that this may be mediated by a ...

When queens and wannabe queens of the species Harpegnathos saltator gear up to reproduce, a part of what’s called the insulin signaling pathway gets blocked, slowing aging, the researchers ...

This protein blocks insulin signaling in different pathway found in fat cells and it's this mechanism that is thought to trigger the incredible lifespan-extending feature of the queen.

A 46-year-old woman with type 2 diabetes was admitted to this hospital because of hyperglycemia for which she was receiving over 2000 units of insulin per day. A diagnosis was made.