The effector functions of natural killer cells are regulated by activating receptors, which recognize stress-inducible ligands expressed on target cells and signal through association with ...

The impact of newly approved drugs on clinical and operational strategies for multiple myeloma clinical trials. Treatment sequencing patterns for relapsed refractory multiple myeloma (RRMM) in the era ...

“The work helped to reveal that activation of IL-15 signaling in pancreatic cancer ... which is designed to enhance IL-15/IL-15Rα pathway signals with reduced potential for harmful inflammatory ...

Ligand-receptor analyzes identified IL-15 signaling in granulomas as a driver of cytotoxic T cells. These data support that CD 8+ lymphocytes are required for early protection against Mtb and ...

IL-15 is one of several types of cytokines - substances that have signaling and regulating functions in immune system activity. "As part of our comparative oncology research, we are strong ...

Preclinical studies showed that the addition of IL-15, which helps T cells survive and multiply, could improve the performance of CAR T cell-based immunotherapies. In these trials, researchers tested ...