Patients with vitiligo experience impacts on quality of life, emerging therapies offer promising prospects for more targeted ...

Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of ...

Discussion: These findings characterize ADP-520 as a first-in-class, CD70-targeted, fratricide-resistant autologous TRuC T-cell therapy leveraging native TCR signaling combined with constitutive IL-15 ...

Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic ...

DNA methylation, RTK pathway changes, and KRAS amplifications may drive resistance to sotorasib plus panitumumab in KRAS G12C ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; "Ono"), today announced that the results from the open label Phase 2 PROSPECT Study of tirabrutinib is to be ...

A rationally designed RNA interference screen was recently used to place DOCK180 in the Rac activation pathway that is controlled by uPAR 19, and RNA interference library screening is a useful ...

Curcumin, a phenolic antioxidant extracted from the rhizomes of turmeric and other Curcuma species, possesses strong ...

Pasritamig, a first-in-class bispecific T-cell-engaging antibody, shows potential in mCRPC with outpatient dosing designed for the community setting ...

A personalised digital care pathway (PDCP) is a tool that facilitates the provision of tailored and timely information. Despite its potential, barriers influence the implementation of digital tools in ...