These two cytokines operate through the IL-1 type I receptor (IL-1RI) on a variety of cell types, inducing expression of an array of proinflammatory proteins such as IL-6, TNF-α, IL-8 ...

Experimental models of gouty inflammation have shown that neutrophil influx in response to MSU crystals is reduced in mice deficient in inflammasome components or in the IL-1 receptor (IL1-R1 ...

offering new insights into the functional roles of this receptor in the central nervous system (CNS). Previous studies conducted by the FAU Quan Laboratory, reveal that chronic IL-1 signaling in ...

offering new insights into the functional roles of this receptor in the central nervous system (CNS). Previous studies conducted by the FAU Quan Laboratory, reveal that chronic IL-1 signaling in ...