The IgA protein is a normal part of the body's immune system. We do not know exactly what triggers the immune system to cause IgA deposits and other immune protein complexes in the glomeruli.

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Sometimes, doctors prescribe tonsillectomy to treat immunoglobulin A (IgA) nephropathy. More research is needed on the potential benefits and risks, including in non-Asian populations ...

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Patients with IgA nephropathy and severe proteinuria have a high lifetime risk of kidney failure. The efficacy and safety of the selective endothelin type A receptor antagonist atrasentan in ...

IgA nephropathy (IgAN) is characterized by the deposition of IgA1-containing immune complexes in the glomerular mesangium. The pathogenesis follows a 4-hit cascade: ...