In Brazil, eight of every 100,000 people under the age of 20 have DM1 (2). The therapeutic treatment and control of DM1 includes the use of insulin for glycemic control, balanced diet, and regular ...

Regular insulin, which is often used in pregnancy for the treatment of diabetes, has some drawbacks: it starts its action from 30 to 60 min after subcutaneous injection and it peaks too late (2-3 ...