Single-cell replication timing (scRT) studies in cancer ... cell lines, and patient-derived xenografts. Knockout of mitochondrial transcription elongation factor, TEFM, in cultured human cells ...

The work implies that the a transposon-derived RNA binding protein in the human genome can interact with the ancestral transposable element from which this protein was initially derived. This work ...

In human embryonic stem cells it is found to be essential for maintaining pluripotency. In cancer, L1TD1 expression ... and transcriptome and thereby reduces cell viability. Notably, L1TD1 associates ...

A research team led by Professor Kevin Tsia, program director of the Biomedical Engineering Program under the Faculty of Engineering of the University of Hong Kong (HKU), has developed an AI-driven ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

A research team led by Prof. Jiang Yanyi from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has uncovered an important mechanism that enables squamous cell carcinoma (SCC ...

Using human cells, researchers developed a 3D experimental model that mimics the development of human bone marrow tissue that can be used to study chemotherapy toxicity.

Cancer cells work together to source nutrients from their environment -- a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...

A gene called high mobility group A1 (HMGA1) may be the key that opens the door to the development of colon cancer, according ...

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...