Takeda licenses late-stage polycythemia vera drug candidate rusfertide from Protagonist Therapeutics, adding to its rare blood disorder pipeline.

Rusfertide, an investigational, first-in-class hepcidin mimetic peptide therapeutic, is under evaluation in the Phase 3 VERIFY study for its potential to regulate iron homeostasis and red blood ...

Summary for Physicians: Hepcidin Mimetics and Their Role in PV—Focus on Rusfertide Hepcidin mimetics, such as rusfertide, represent an innovative approach to managing polycythemia vera (PV), ...

ABSTRACT: Background: Hepcidin is the principal regulator of iron absorption and its tissue distribution. Its correlation with iron homeostasis in individuals infected with human immunodeficiency ...

Rusfertide: A Novel Approach to Iron Regulation Hepcidin is the master regulator of systemic iron homeostasis. It controls iron through ferroportin, a transmembrane protein responsible for delivering ...

During the two decades that lapsed since “ironome” was coined for the ensemble of proteins associated with iron metabolism, a surge of iron-driven biological processes have been recognized as ...

Iron Maiden kicked off their Run for Your Lives 50th anniversary tour on May 27, 2025.

Iron deficiency is more common in women than in men, and it often goes undiagnosed. Doctors share the top signs of an iron deficiency and ways you can treat it.

The Harley-Davidson Iron 883 was a fan-favorite, thanks to its unique build and affordable price point. So why did the company decide to discontinue it?