Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Specifically, we introduce R-chain, which is based on a chain structure to build related metapath instances together. We can efficiently reuse vertices through R-chain and process different R-chains ...

Nanobodies are promising therapeutic agents due to their superior biological properties. Given the importance of binding affinity, a computational model capable of generating high-affinity nanobodies ...

Heavy Chain Engineering is a solopreneur-led consultancy that partners with founders, small businesses, and lean teams to bring digital products to life. We cut through ambiguity, get moving quickly, ...

Leveraging Complementary Ion Activation Methods with Proton Transfer Charge Reduction Reactions for Comprehensive Characterization of Monoclonal Antibody Heavy Chain ...

More than half a dozen businesses were burglarized during street takeovers in Bellflower and Lakewood overnight, the L.A. County Sheriff’s Department says. It was around 1:50 a.m. Saturday w… ...

A community is outraged after a man who has been selling ice cream in Culver City for nearly 20 years was detained by immigration agents. On June 23, Ambrocio Lozano, also known as Enrique, was set… ...

NEW YORK — Zohran Mamdani has claimed victory over a wounded, but still formidable former Gov. Andrew Cuomo in New York City’s Democratic mayoral primary. Now he faces an equally tough task ...

Air Warfare, Global, Land Warfare, missile defense, Space US Space Command’s Gen. Whiting talks Golden Dome, EW and China’s space-based kill chain One area where China has "moved ...