Remember "Plop, plop, fizz, fizz, oh what a relief it is"? Well, heartburn drugs have changed a lot since that TV jingle became popular. Americans spent $6 billion on the acid-reflux drug Nexium ...

and this has led to an overuse of the drugs in the treatment of garden-variety heartburn. PPIs are among the highest-selling classes of drugs in the U.S., with $9.5 billion in sales last year ...

These 15 home remedies can ease your heartburn discomfort without the worrisome side effects. Here's what you need to ...

Baking soda is also high in sodium, which may interfere with the absorption of some medications. Heartburn can be uncomfortable, but there are a number of home remedies that may help. Sleeping ...

Medications ... reduce heartburn episodes in patients with non-erosive GERD. PCABs are not routinely used in the United States and are not recommended as a first-line drug treatment for GERD ...