MORE: Reese Witherspoon wishes her mom a happy birthday: 'Please keep bringing sunshine into our lives' "Happy 50th birthday to my big Bro John!!" she wrote in the caption of the post.

Witherspoon, 46, has wished John a happy birthday on social media in the past. Last year, she celebrated John's birthday by thanking him for being her "biggest supporter." Next to an Instagram pic ...

To quote the great poet 50 Cent, “We gon’ party like it’s your birthday!” Birthday Wishes for Your Brother-In-Law Happy birthday to my favorite non-blood relative!

As a kid, I was the youngest of four boys. I wasn’t considered a younger brother, I was considered a moving target.” Reynolds has a long history of creative and hilarious happy birthday messages.

Good morning everyone, and what a lovely start to the new year it is, because it’s your birthday! Happy birthday, it’s your 50th! What’s that you say, you aren’t 50 today? (… ...

Gumby, the little green clay boy, is celebrating 50 years in show business — in 1956 he made his first appearance on television on “The Howdy Doody Show” — and he’s lo… ...

Happy 50th birthday, Barbie! Adults say collecting popular dolls brings back memories Published: Mar. 09, 2009, 11:51 a.m. By Dave Person | Special to the Kalamazoo Gazette ...