The structure of ribosomal protein S7 at 1.9 Å resolution reveals a beta-hairpin motif that binds double-stranded nucleic acids. Structure 5, 1187– 1198 (1997).

Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...

Basecamp says that BaseFold builds on that model, which predicts the 3D structure of a protein based on its amino acid sequence, by layering in a foundational dataset (BaseGraph) that considers ...

Proteins are essential for life, and their structure determines their function. The protein secondary structure is formed by the folding of the protein primary structure, and the protein tertiary ...

Protein–protein interactions are no longer considered undruggable because of the conceptual and technical advances that allow inhibitors to be generated using rational design principles and ...

Encapsulating biomacromolecules within metal–organic frameworks (MOFs) can confer thermostability to entrapped guests. It has been hypothesized that the confinement of guest molecules within a rigid ...

ABSTRACT: In modern astrophysics, it is believed that galaxies are not expanding. The authors of the article set out to investigate the motion of Globular Clusters (GC) of the Milky Way relative to ...

Furthermore, the RNA stop assays and the EGFP expression inhibition experiments highlighted the effect of a stable G4 structure of PQS1 in inhibiting RNA replication (Figure 4—figure supplement 1) and ...