FLAIR imaging showed a central hypointense signal with a slightly hyperintense peripheral rim, without restricted diffusion, suggesting a possible area of focal encephalomalacia with gliosis or ...

Reactive gliosis, strong upregulation of microglia and multiple macrophages around the blood vessels in both white and grey matter were present (Figure 2C, D).

When the brain is injured in some way, a wide range of biochemical changes are triggered that can affect crucial brain cells known as astrocytes. They are a type of glial cell, and brain injuries ...

Explore the new research on caffeine infant and its potential role in preventing Sudden Unexpected Infant Death and SIDS.

UT Southwestern Scientists have identified the protein GADD45G as a master regulator of reactive gliosis, a damaging process in neurodegenerative diseases like Parkinson's.

Hypothalamic gliosis is mechanistically linked to obesity and insulin resistance in rodent models. We tested cross‐sectional associations between radiologic measures of hypothalamic gliosis in humans ...

New research suggests that concussions and repetitive head trauma may reactivate dormant viruses like HSV-1 in the brain, potentially triggering neurodegenerative diseases such as Alzheimer’s.

Alzheimer's disease is a multifactorial neurodegenerative disorder, characterized by amyloid plaques, neurofibrillary tangles, and gliosis. Beyond genetic and age-related factors, diverse risk ...

Impaired mitochondrial protein import machinery leads to phenotypically heterogeneous diseases. Here, we report a recurrent homozygous missense variant in the gene that encodes the translocase of ...