Alexander starred on “General Hospital” on and off for almost 50 years. Lesley was killed in 1984 and then resurrected in 1996. Alexander’s last appearance on the soap was in 2021.

Denise Alexander, who portrayed Dr. Lesley Williams on "General Hospital" for nearly five decades, died at the age of 85. (Getty Images) Fans were quick to share their sympathies as well.

Soap opera veteran Denise Alexander, best known for her starring roles on 'General Hospital' and 'Days of Our Lives', has died at the age of 85.

She was 85 age. General Hospital Executive Producer Frank Valentine took to X to pay tribute to the actress stating "I am so very sorry to hear of Denise Alexander’s passing.

Soap opera star Denise Alexander, known as Lesley Webber on "General Hospital" and Susan Hunter Martin on "Days of Our Lives," has died. She was 85.

Denise Alexander, best known for her decades-long portrayal of Dr. Lesley Webber on “General Hospital,” has died. She was 85. Alexander reportedly died in March. No further details were given.

Denise Alexander, Susan Seaforth Hayes in "Days of Our Lives" in 1971.© NBCU Photo Bank/NBCUniversal via Getty Images Denise Alexander attends the Hollywood Sign's 90th Anniversary in 2013 ...

General Hospital showrunner Frank Valentini, 62, shared news of her passing via a statement posted to X. “I am so very sorry to hear of Denise Alexander’s passing. She broke barriers on-screen ...

Soap opera star Denise Alexander, best known for playing “General Hospital’s” Lesley Webber, has died at age 85. The actress — who also played Susan Hunter Martin on “Days of Our Lives ...