Researchers have discovered how the C. diff toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections.

demonstrated the Singulex Clarity C. diff toxins A/B assay yielded 98% sensitivity and 100% specificity compared to multistep PCR-and-toxin testing. It was concluded that the assay is ...

The work, led by Min Dong, PhD, and Liang Tao, PhD, of Boston Children's Hospital, reveals how the bug's most potent toxin gets into ... cause of death from GI illness. C. diff tops the CDC's ...

The toxin-A- and toxin-B-specific ... were transferred by conjugation to C. difficile strain JIR8094 and the resultant chromosomal mutants analysed by PCR, Southern blotting and plasmid rescue ...

This abstract tackles some of these. The authors studied the kinetics of PCR positivity in C. diff and whether test positivity during or after treatment was a marker for recurrence. The average ...

Patients who were missing components for recurrent C. difficile infection criteria (for example, having a positive toxin test result) were also counted as reinfected. Limitations included that the ...

Included patient encounters had a positive C difficile PCR test and either a toxin EIA-positive assay (confirmed cases) or toxin EIA-negative assay (controls). Available encounter stool specimens ...

A new study encompassing nearly 40,000 hospital visits from a geographically diverse healthcare database shows that sampling a single stool, using multiple polymerase chain reaction (PCR ...