Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...

Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative anti-inflammatory and ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Septerna, Inc. (Nasdaq: SEPN), a biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey Finer, M.D., Ph.D., Chief Executive ...

Penn researchers create mirror-image molecules that both kill pathogens outright and rally the immune system – an advance ...

Researchers have captured a time-resolved video of a protein interaction essential to healthy brain development.

Pheochromocytomas and paragangliomas (PCPG) are highly vascular neuroendocrine tumors originating from chromaffin cells of ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

Petosemtamab is projected to reach $1.2bn in global sales by 2030, while ficerafusp alfa will reach $620 million.

N/OFQ activates a G i-protein-coupled receptor, NOP, and this peptide–receptor system has been implicated in a diverse range of biological functions including (but not limited to) pain ...

For athletes and active adults who don’t eat animal products, getting adequate protein from diet alone can be challenging. A vegan protein powder may help. Our dietitians vetted more than a ...