Transcription factors can increase and decrease gene expression, and sometimes work with protein partners to do so; they tend to have an end that can bind to DNA and another end that can attach to ...

Weaker transcription factors are better when they work together Date: August 15, 2023 Source: Rice University Summary: Bioengineers have developed a generalizable method to address 'off-target ...

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that ...

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

Transcription factors are proteins that bind to specific DNA sequences to control gene expression, guiding cells to become ...

Transcription factors (which are described in the video) have to be able to first scan the genome so they can find their target sites and then bind there, which will turn genes on or off. It's known ...

Transcription factors are critical proteins that regulate gene expression, playing a pivotal role in controlling key processes such as lipid metabolism, inflammation, apoptosis, and fibrosis in MAFLD.

Flare Therapeutics has launched with $82 million in series A financing to discover small-molecule drugs that target transcription factors implicated in cancer. The life science venture capital ...

Studying the expression of these transcription factors in patients with colorectal cancers could reveal biomarkers to help determine overall survival in people with a subgroup of colorectal ...

If this transcription pattern is disrupted, the cells become more like helper T cells, GW Today reported. This previously unknown function of Tcf1 and Lef1 represents a potential drug target for ...

Prof. Buganim stated, "By uncovering how transcription factors interact with chromatin architecture, we can better understand gene regulation and cellular identity. This knowledge opens exciting ...