Fibrous dysplasia is a rare, mosaic disorder that leads to fractures, pain, and disability. Gain-of-function GNAS variants alter skeletal stem-cell differentiation, which results in the formation ...

"This trial is the culmination of 25 years of clinical research at NIDCR to understand the underlying mechanisms of fibrous dysplasia and to identify promising treatments," said NIDCR Director ...

Ectodermal dysplasia: The different types of ectodermal dysplasia affect the hair, teeth, nails, skin, and sweat glands in different ways. Symptoms can include brittle hair, abnormal teeth ...