Anthraquinone-fused enediynes are anticancer natural products featuring a DNA-intercalating anthraquinone moiety. Despite recent insights into anthraquinone-fused enediyne (AQE) biosynthesis, the ...

Benzene’s physical properties only added to its mystique. This colourless liquid emitted a faintly sweet, intoxicating aroma – a hallmark of aromatic compounds. With a boiling point of 80.1°C, it was ...

C&EN’s Year in Chemistry 2021 With researchers back in the swing of things, we review the year’s top trends, fascinating findings, memorable molecules, and more ...

Natural product biosynthesis is nature’s tinkering ground for developing new enzymes that can achieve chemical transformations that are outside the purview of traditional chemical catalysis. Herein we ...

A breakthrough study has validated the existence of a stable single-electron covalent bond between two carbon atoms, supporting Linus Pauling's early 20th-century theory and opening avenues for ...

Obsidian's built-in table syntax can only define the basics for tables. When users try to apply complex tables with colspan or multiple headers, their only option is to fall back to raw HTML, which is ...

Immunometabolism is an emerging field at the intersection of immunology and metabolism. Immune cell activation plays a critical role in the pathogenesis of cardiovascular diseases and is integral for ...

Central to mitochondria function is the tricarboxylic acid (TCA) cycle or Krebs cycle: It starts with the combination of acetyl-CoA, derived from carbohydrates, fats, and proteins, with oxaloacetate ...

Abstract Tyrosine kinase inhibitors (TKIs) are a novel category of antitumor agents with remarkable efficacy in extending patient survival. However, clinical use of TKIs has been hindered by the major ...

The energy for various functions of the human body comes from the nutrient molecules that have been metabolised. In fact, the main purpose of food intake is supply of energy. This energy comes ...