Innovative Microscopy Tool Provides a New Way To See What Lies Between Cells
Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, ...
Science Daily11d
Looking between cells
Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...
Looking between cells: Light microscopy probe provides unprecedented view of extracellular matrix
Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...
eLife13d
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...
eLife11d
Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal Model
Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...
Medscape12d
Promise for CAR T-Cell Therapies in Solid Tumors?
CAR T-cell therapies have demonstrated efficacy in treating blood cancers but, so far, their safety and effectiveness in ...