Following treatment, the AAV-Navβ1 vector successfully expressed the β1 subunit protein in both excitatory and inhibitory neurons ... therapeutic levels of mRNA and protein expression in ...

Researchers measure gene expression by observing the amount of mRNA a specific gene produces ... We relied on six well-established major cell types: excitatory and inhibitory neurons, astrocytes, ...

These somatostatin (SST) inhibitory neurons usually send calming signals to other cells. The study authors suggest that the loss of these neurons might trigger the subsequent brain changes that ...

From there they can be further sorted into subclasses: Excitatory neurons are categorized by the layer of the brain they’re in while inhibitory neurons are identified by the marker proteins they ...

The data collected and the methods used by the authors are solid and the authors suggest that V2 excitatory and inhibitory neurons have antagonistic functions ... with labeled Hes2 mRNA (red) and ...

and the expression levels of cell-type marker genes. Results: The culture of fetal prefrontal cortex tissues obtained at gestation weeks 11 and 20 predominantly consisted of excitatory and inhibitory ...

The activation of translation by reducing p-eIF2α in excitatory and somatostatin-positive inhibitory neurons enhances memory consolidation ... In conclusion, our findings underscore the role of mRNA ...

Schizophrenia-associated SST mRNA elevations have been reported in both posterior ... excitation and inhibition signals is different in various subtypes of excitatory or inhibitory neurons and global ...

Brain renin angiotensin system within the paraventricular nucleus plays a critical role in balancing excitatory and inhibitory ... mRNA expression was significantly higher. 34 Accordingly, ACE2 ...