Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

The Itovebi (inavolisib)-based regimen reduced the risk of death by more than 30% in people with PIK3CA-mutated HR-positive, HER2-negative advanced breast ...

Using high-speed atomic force microscopy (HS-AFM), Richard Wong and colleagues at Kanazawa University directly visualized how the estrogen receptor alpha (ERα) binds to DNA and switches on genes in ...

Using high-speed atomic force microscopy (HS-AFM), Richard Wong and colleagues at Kanazawa University directly visualized how the estrogen receptor alpha (ERα) binds to DNA and switches on genes ...

As I said, they degrade estrogen receptor alpha in a dose-dependent manner. They inhibit estrogen-directed gene transcription and tumor growth, and they have better pharmacokinetic properties ...

Summary: Researchers have discovered that estrogen’s fast action on neurons is mediated by the estrogen receptor-alpha (ER-alpha) coupling with the chloride ion channel Clic1. This interaction allows ...

researchers discovered that estrogen’s fast actions are mediated by the coupling of the estrogen receptor-alpha (ER-alpha) with an ion channel protein called Clic1. Clic1 controls the fast flux of ...

Researchers discovered a mechanism by which estrogen can trigger fast neuronal responses. Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a ...

Females had less inflamed plaques, unchanged by EC-MR-knockout (KO). Hypothesis: We hypothesized that EC-estrogen receptor alpha (ER) protects females from plaque inflammation by inhibiting NFkB and ...

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