Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

In parallel, exposure to naringin enhanced translocation of estrogen receptor alpha (ERα) to nuclei and its transactivation activity. Sequentially, naringin induced alkaline phosphatase (ALP) mRNA and ...

But eventually, the cancers were expected to mutate and defy the standard drugs, often by altering their estrogen receptor so it signals the cancer cells to grow without ever binding to estrogen.

The Itovebi (inavolisib)-based regimen reduced the risk of death by more than 30% in people with PIK3CA-mutated HR-positive, HER2-negative advanced breast ...

Our analysis of ecdysone-induced downstream targets reveals that overexpression of the nuclear receptor E75, particularly facilitates the malignant transformation of benign tumors. Genome-wide DNA ...

Supported by Pfizer in collaboration with Arvinas Estrogen Receptor. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. We thank the patients ...

Not all medicines and/or indications presented in this report may be approved for use in all countries. Please note data included in this report are based on EU data and may vary depending on local ...

Following the TGE, RDO will be available for Binance Alpha trading on PancakeSwap and Binance Wallet DEX, providing access across both decentralized and semi-custodial venues. As part of its ...