Researchers at Vanderbilt University identified a molecular approach to extend the antidepressant effects of ketamine in mice by applying BCI, a compound that inhibits DUSP6 to sustain ERK pathway ...

The president suggested Catholics, who have criticized the apparently A.I.-generated image, were not offended, and said that anyone who was “can’t take a joke.” By Aishvarya Kavi Reporting ...

The new Firefly Image Model 4, Adobe says, improves on its predecessors in terms of quality, speed, and the amount of control over the structure and style of outputs, camera angles, and zoom.

Neo-1 is the first model to unify de novo molecular generation and atomic-level structure prediction in a single model, by generating latent representations of whole molecules instead of ...

However, Spravato contains a different form of ketamine than the version that is used intravenously—a chemical sibling called esketamine. In the years since its approval, Spravato and ketamine ...

Moreover, at one and two weeks post-infusion, ketamine failed to beat either the saline or the active placebos. Why was the FDA approval of esketamine so controversial among many researchers?

Prior ketamine or esketamine users were excluded. Other exclusion criteria included non-responsiveness to electroconvulsive therapy for the current episode, vagal nerve or deep brain stimulation ...

The unpatentability of generic ketamine has slowed the process for FDA approval of ketamine for use beyond anesthetic. The inferior molecule of ketamine — SPRAVTO or esketamine ... ketamine’s ...

The discovery of esketamine, essentially a mirror image of the ketamine molecule ... primarily due to the distinct molecular structure of esketamine, which is the S-enantiomer of ketamine. This ...

Looking Back in Time Ketamine was synthesized in 1962 (a mixture of two mirror-image molecules ... Mental Health for their discovery leading to esketamine. A Special Controlled Program The ...