Spravato (esketamine) is a nasal spray used for depression and was approved by the FDA in 2019. It is specifically for treatment-resistant depression, meaning depression symptoms that have not ...

Esketamine administered intravenously during elective cesarean delivery may significantly reduce depressive symptoms in the early postpartum period, according to study results published in JAMA ...

Esketamine nasal spray, administered in combination with either a selective serotonin reuptake inhibitor (SSRI) or a serotonin–norepinephrine reuptake inhibitor (SNRI), is the only treatment ...

Ketamine has a long and varied past as a pharmaceutical. It was developed in 1962, tested on subjects in 1964 and approved as an anesthetic in 1970 in the United States. Ketamine was used in the ...

Budapest, Hungary — A single dose of intravenous esketamine during delivery or caesarean section appears to reduce the risk for postpartum depression (PPD) by more than 50% in the first 6 weeks ...

In the study, 336 adults with treatment-resistant depression were randomly assigned to receive nasal esketamine in addition to the antidepressant medication they were already taking, either a ...

The researchers found a 74% reduction in the risk for postpartum depression in the group that received esketamine (6.7% vs 25.4%). Depression scores on the Edinburgh Postnatal Depression ...

A single low dose injection of esketamine given immediately after childbirth reduces major depressive episodes in individuals with depressive symptoms during pregnancy (prenatal depression), finds ...

The Food and Drug Administration (FDA) has expanded its approval of a ketamine nasal spray, Spravato (esketamine), as a standalone therapy for adults with treatment-resistant depression. Spravato ...

Treatment-resistant depression in older adults is common and can be difficult to manage. Strategies include ensuring adequate antidepressant therapy and addressing concomitant psychiatric and medic ...

New hope for treatment-resistant depression. Understanding what emotional intelligence looks like and the steps needed to improve it could light a path to a more emotionally adept world.