The present study demonstrates modulatory actions of estrogen in transactivations of SXR-mediated liver X receptor response element (LXRE) and CAR-mediated phenobarbital response element (PBRU).

A BUSY HORMONE:© 2001 Annual ReviewsEstrogen's direct genomic effects are mediated by the nuclear form of the estrogen receptors ERα or ERβ which associate with the Estrogen Response Element (ERE) or ...

The recent cloning of a second estrogen receptor (ER), designated ERβ, has prompted a reevaluation of the role of ERs in breast cancer. We have developed and validated a real-time RT–PCR assay ...

Estrogen-bound estrogen receptor (ER), in complex with coactivators (CoA) or corepressors (CoR), regulates target gene expression via the estrogen response element (ERE) or the AP1 binding sites via ...

ERE = estrogen response element RING = A-ring or D-ring metabolic pathway COMT= catechol-O-methyltransferase (COMT) gene. The ERs are ligand-activated transcription factors.