granulocyte–macrophage and macrophage progenitors and, rarely, eosinophil progenitors. As shown by the data in Table 2, summation of colony numbers developing even with two stimuli, such as GM ...

ECP is a marker of the activity and turnover of the eosinophil granulocyte. [4] Our study was designed to examine P-ET levels in paediatric patients newly diagnosed with mild persistent bronchial ...

Recently, the use of mobilizing agents such as granulocyte colony-stimulating factor has renewed interest in these treatment modalities. Some studies have shown a benefit in neutropenic patients ...

Meanwhile, investigation into biomarkers such as CD4 and CD8 T cells, white blood cells, eosinophil count, lymphocyte or monocyte count, and interleukins (ILs) has not provided adequate answers ...

Molgramostim reduced surfactant burden as measured by ground-glass opacification (GGO) scores, a radiological measure of surfactant burden. The mean reduction in GGO score from baseline to Week 24 ...

Emrelis is the first FDA-approved treatment for previously treated patients with locally advanced or metastatic non-squamous non-small cell lung cancer with high c-Met protein overexpression. The FDA ...

Drilling down into the data, however, there was a 37% reduction in exacerbations in a subgroup of patients with a baseline eosinophil count (BEC) 150 cells/μL or more, a population that Amgen and ...

METREX involved patients with a range of eosinophil levels and showed a statistically significant improvement for Nucala versus placebo on exacerbation rates. However, in METREO – which focused ...

Chronic myeloid leukaemia (CML) is a type of cancer that affects the blood and bone marrow. The leukaemia develops from early blood cells called myeloid blood stem cells. CML usually develops very ...

Among patients without CB, no effect was seen in those with low BECs, but a 56% reduction was observed in the elevated eosinophil subgroup. These findings underscore the role of type 2 inflammation, ...