The endoplasmic reticulum (ER) is a compartment (organelle) in eukaryotic cells that consists of membrane sacs called cisternae. Because of the bound ribosomes, the 'rough' ER is the site of ...

Hemifusomes are fused vesicles, or sacs of fluid, that were previously unknown to exist inside cells. They were discovered ...

A further understanding of the organelle could pave the way for better treatment of genetic and neurodegenerative diseases.

Owing to the toxic potential of unfolded proteins, their accumulation in the endoplasmic reticulum activates a cellular stress response. This unfolded protein response remodels the secretory ...

Scientists have made a groundbreaking discovery in the realm of human cell biology. Through the use of cryo-electron ...

The endoplasmic reticulum (ER) is the most metabolically active organelle in cells, and recent research has shown that abnormal ER function is involved in the occurrence and development of acute ...

The endoplasmic reticulum (ER) is essential for multiple cellular functions, including protein synthesis and transportation, biosynthesis of lipids, and calcium homeostasis (Hotamisligil 2010). Hence, ...

The identification of SLC35F2 as the eukaryotic transporter of queuine and queuosine is key to understanding how these micronutrients are salvaged from the human gut and distributed to different body ...

This important study presents compelling observational data supporting a role for transcription and polysome accumulation in the separation of newly replicated bacterial chromosomes. Through a ...

The lactate indicator was not significantly affected by Ca 2+ at the physiological concentrations prevailing in the cytosol, endoplasmic reticulum, and extracellular space, but was affected by Ca 2+ ...