Furin is identified as the key enzyme responsible for cleaving the apelin precursor. Inhibiting this cleavage could serve as ...

College of Food Science and Engineering, Northwest A&F University, Yangling 712100, P. R. China ...

Aldehydes are capable of modifying DNA and yielding promutagenic lesions, which may, at least partially, account for the observed mutagenic and carcinogenic effects associated with the lipid ...

Therefore, the researchers believe that this biological system, its receptors, pathways, and ligands might be considered as an auxiliary compound to reduce the number of patients suffering from ...

Indeed, oxidation damage is highly dependent on the inherited or acquired defects in enzymes involved in the redox-mediated signaling pathways. Therefore ... and subsequently promoting healthy ...

Depletion of PEBP1 impaired mitochondrial ISR activation by reducing eukaryotic translation initiation factor 2α (eIF2α) phosphorylation and subsequent ISR gene expression, which was independent of ...

Lipid nanoparticles (LNPs) represent a highly promising nonviral delivery platform for a variety of therapeutic nucleic acids, including short interfering RNA (siRNA), mRNA (mRNA), single-guide RNA ...