Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after ...

“DNA damage in cells induces the expression of inflammatory genes,” the researchers wrote. “However, the mechanism by which cells initiate an innate immune response in the presence of DNA ...

When DNA inside the nucleus of a human cell is damaged, a specific network of microtubule filaments form s in the cytoplasm around the nucleus and pushes on the nuclear envelope.

Looking ahead, he hopes to apply transposon-based systems to gene editing. Peters explained that many genetic diseases have single nucleotide errors in the DNA sequence.

Breakthrough molecular movie reveals DNA's unzipping mechanism with implications for viral and cancer treatments Date: March 20, 2025 Source: University of Leicester Summary: Scientists have ...

DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH When cells in the human body divide, they must first make accurate copies of their DNA.

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair ...

"DNA replication mechanism in pluripotent stem cells." ScienceDaily. ScienceDaily, 19 August 2024. <www.sciencedaily.com / releases / 2024 / 08 / 240819130729.htm>.

Sharing the motivation behind their study, Prof. Shinohara explains, “The mechanism by which Sae2 stimulates the MRX endonuclease and 3’-5’ exonuclease activities for DNA repair remains unknown.

New research uncovering the DNA-damaging mechanism by which a mutated gene causes a rare, fatal disease may have repercussions for the treatment of many other diseases linked to aging, including ...

Causes of unique DNA organization in early embryos Using these techniques, called scDam&T-seq and EpiDamID, the researchers found that DNA regions that are not located near the nuclear edge have ...