We’ve found a way that Mycobacterium tuberculosis can slow down its growth and potentially allow it to hide from the immune response and resist antibiotics. By showing that ADP-ribosylation of DNA can ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

DNA organization offers clues for advancing stem cell therapy. UC Riverside-led study could help advance treatments for injuries, aging, ... The paper is titled “Histone Chaperones Coupled to DNA ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Transcription and DNA replication collisions lead to large tandem duplications and expose targetable therapeutic vulnerabilities in cancer. November 25, 2024 In the present study, we used 6,193 ...

When these pathways are activated, DNA replication is suppressed at sites in the genome called origins; at the same time, the progression of DNA replication forks also slows down. Replication forks, ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

When these pathways are activated, DNA replication is suppressed at sites in the genome called origins; at the same time, the progression of DNA replication forks also slows down. Replication forks, ...

From chromosome to deoxyribonucleic acid structure and base pairing. DNA Replication diagram. DNA Polymerase enzyme syntheses. Synthesis of leading strand and lagging strand during DNA replication. ..

The G4-DNA structure can therefore be involved in both the enhancement and impairment of transcription in active neurons, based on their activity, to enable different memory states.

The G4-DNA structure can therefore be involved in both the enhanced and impairment of transcription in active neurons, based on their activity, to enable different memory states.