Trial in progress: First-in-human study of PFL-721/STX-721 in participants with locally advanced or metastatic non-small cell lung cancer harboring EGFR exon 20 insertion mutations. This is an ASCO ...

At the heart of this method lies the Bst DNA polymerase, whose enzymatic properties—such as strand displacement activity, thermostability, and catalytic efficiency—are critical to the success ...

The case went cold for decades, until a breakthrough in 2023 when investigators matched DNA evidence from the rape kit to Washington, cleveland.com and The Plain Dealer reported. Once Washington ...

While authorities speculated it may be Ndlovu and Mdhluli, DNA tests are yet to be concluded. - Families of Aserie Ndlovu & Zodwa Mdhluli say their lives in limbo as they wait for DNA results The ...

Forensic DNA profiling relies on amplifying short tandem repeats via polymerase chain reaction (PCR). However, during PCR, DNA polymerases can slip on these repeats, producing "stutter" ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

COURTHOUSE IN DEDHAM RIGHT NOW. DAVID. GOOD EVENING MARIA. WE WATCHED AS THE FACE OF THIS EXPERT BECAME REDDER AND REDDER AS HE WAS FORCED TO DEFEND HIS CREDIBILITY AND HIS HONESTY. BUT HE STUCK ...

Scientists have uncovered fast-changing DNA regions using new sequencing tech, reshaping our understanding of human genetics and inherited disease. Rapidly mutating DNA regions were mapped using a ...