By uncovering RNA’s previously unknown function to repair DNA damage, our findings show how RNA may directly contribute to the stability and evolution of the genome.

By uncovering RNA’s previously unknown function to repair DNA damage, our findings show how RNA may directly contribute to the stability and evolution of the genome.

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can ...

More information: Keiko Iwata et al, Genome‐wide DNA methylation profiles in the raphe nuclei of patients with autism spectrum disorder, Psychiatry and Clinical Neurosciences (2025).

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease1.

PacBio (Nasdaq: PACB), announced it plans to improve on its already highly accurate methylation detection capabilities in HiFi chemistry through licensing advanced DNA methylation detection methods ...

PacBio enhances HiFi sequencing with AI-based methylation detection, enabling accurate native 5hmC and strand-specific 5mC analysis.

PacBio enhances methylation detection in HiFi sequencing by licensing advanced methods, improving insights into DNA modifications.

Company licenses novel deep learning-based epigenetic models from CUHK enabling the detection of 5hmC, 5mC hemimethylation, and 6mA in standard sequencing runs MENLO PARK, Calif., April 28, 2025 ...

Another form of DNA methylation, 6mA, was erroneously reported by other researchers in several organisms before its detection was traced to bacterial contamination.

Horizontal gene transfer Another form of DNA methylation, 6mA, was erroneously reported by other researchers in several organisms before its detection was traced to bacterial contamination.

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.