For patients without and with PE, the median D-dimer values were 1.0 and 6.1 µg/mL, respectively; D-dimer values ranged from 0.2 to 128 µg/mL and from 0.5 to more than 10,000 µg/mL, respectively.

Study: Diagnostic accuracy of age-adjusted D-dimer for pulmonary embolism among Emergency Department patients with suspected SARS-COV-2: A Canadian COVID-19 Emergency Department Rapid Response ...

An international systematic review and individual-patient data meta-analysis (IPDMA) from over 20,000 patients with suspected pulmonary embolism (PE) shows that diagnostic strategies for ruling ...

Bannelier, H., et al. (2024). Failure rate of D‐dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies.

Of 674 patients without a high probability of pulmonary embolism, 232 (34%) had a negative D-dimer assay and an uneventful follow-up, and 109 patients had CT evidence of pulmonary embolism. Of 318 ...

A negative D-dimer test (one that rules out pulmonary embolism) can help patients avoid more expensive, invasive diagnostic tests, like a computed tomography pulmonary angiogram, or CTPA.

A pulmonary embolism (PE) diagnostic strategy using a higher D-dimer threshold under the so-called YEARS rule combined with age adjustment for selected patients who couldn't be ruled out by PE ...

For patients with suspected pulmonary embolism, diagnostic strategies to rule out PE that apply adapted D-dimer thresholds were safe and efficient, even in high-risk patients.Researchers reported ...

Combining the Wells rule and a POC yielded a sensitivity and specificity of 94.5% and 51.0%, respectively, which when combined with a quantitative test changed to 98.6% and 47.2%, respectively.

Since normal D-dimer levels increase with age, physicians should use age-adjusted D-dimer thresholds (age times 10 ng/mL rather than a generic 500 ng/mL) in patients older than 50 years to ...

The combination of a simple clinical decision rule, D-dimer testing, and computed tomography is as effective as other, more complex, diagnostic strategies and is associated with a low risk for ...

Since its introduction to clinical use, the D-dimer test for deep venous thrombosis/pulmonary embolism has been a blessing and a curse. What is the current thinking regarding D-dimer use in ...