They also make cholesterol-dependent cytolysin-like (CDCL) toxins, which can poke holes in other microbes, causing them to die. But CDCL is only used when Bacteroides touch another bacteria, and they ...

Researchers at the University of Oklahoma have found that gut bacteria produce toxins that can selectively attack cancer cells, offering a new potential strategy for treating cancer.

University of Oklahoma researchers have discovered that some bacteria in the gut have their own unique “weapon system” to compete against other bacteria for dominance. Importantly, there is promising ...

In response to this discovery, Arm & Hammer Animal Nutrition developed a multiplex PCR (mPCR) assay that enables high-throughput screening of E. faecalis isolates for the PAI and cytolysin genes.

Researchers are one step closer to slowing the spread of Enterococcus faecalis in poultry hatcheries with the discovery of a potential virulence factor. E. faecalis is a gram-positive bacterium that ...

Oncomatryx has acquired Tube Pharmaceuticals GmbH, the developer of the Cytolysin toxic payload. The multimillion €uros transaction is a strategic dec ...

Oncomatryx has acquired Tube Pharmaceuticals GmbH, the developer of the Cytolysin toxic payload. The multimillion €uros transaction is a strategic decision by Oncomatryx that will foster its ...

ZAMUDIO, Spain--(BUSINESS WIRE)-- Oncomatryx has acquired Tube Pharmaceuticals GmbH, the developer of the Cytolysin toxic payload. The multimillion €uros transaction is a strategic decision by ...

Determining the free energy landscape of these membrane driven transitions remains a challenging problem. Although cholesterol recognition is required for lytic activity of several proteins in the PFT ...

Enterococcus faecalis is one of the major causes for hospital‐acquired antibiotic‐resistant infections. It produces an exotoxin, called cytolysin, which is lethal for a wide range of Gram‐positive ...

Several bacterial infections are mediated by pore-forming toxins (PFTs), a subclass of proteins that oligomerize on mammalian cell membranes forming lytic nanopores. Cytolysin A (ClyA), an α-PFT, ...

Attacking Cancer With Light-Controlled Bacteria? Synthetic Biology: A team of undergraduates program bacteria to release toxic payload in response to blue or red light, possibly paving the way for ...