IFLScience on MSN11h
Inhalable Cystic Fibrosis Gene Therapy 24 Years In The Making Enters Clinical Trials
A new inhalable gene therapy for cystic fibrosis (CF) has entered Phase I clinical trials, a major milestone on the journey ...
EurekAlert!2d
Novel inhalable gene therapy trialled for people with cystic fibrosis
An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis, irrespective of their mutation type, is being tested in human trials in the UK and Europe.
BioWorld2d
Trial begins for inhaled gene therapy for cystic fibrosis
The longstanding ambition of developing an inhaled gene therapy for cystic fibrosis has taken a step forward, with the start of a phase I/II trial of a product using a novel pseudotyped viral vector ...
Boehringer Ingelheim and partners start clinical development of a first-in-class, inhaled gene therapy for people with cystic fibrosis
Boehringer Ingelheim, IP Group, the UK Respiratory Gene Therapy Consortium (GTC) 1 and OXB, 1 today announce the start of LENTICLAIR TM 1, a Phase I/II trial of BI 3720931, a novel, first-in-class, ...
Medscape3d
Novel Triple Combination Therapy May Transform Cystic Fibrosis Care in Children
Once-daily vanzacaftor-tezacaftor-deutivacaftor was safe and well-tolerated in children with cystic fibrosis, while ...
Science Daily7mon
Cystic Fibrosis News
Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis ... Nov. 14, 2022 — Researchers have developed a simple urine test to measure the severity ...
precisionmedicineonline1d
Boehringer Ingelheim Kicks Off Inhaled Cystic Fibrosis Gene Therapy Phase I/II Trial With Partners
Boehringer Ingelheim, IP Group, UK Respiratory Gene Therapy Consortium, and OXB launched the first-in-human clinical trial, known as LENTICLAIR 1.
The Lancet9d
Patient with cystic fibrosis not diagnosed until age 23 years now treated with the new triple therapy Trikafta
The effect of cystic fibrosis on many organs and the frequent lung infections means that it is mostly diagnosed in childhood.
Medscape4y
Cystic Fibrosis Gene Therapy: Successes, Failures and Hopes for the Future
Cystic fibrosis (CF) is a single-gene disorder with ... Thus, it is not surprising that in the early years of gene therapy, CF was at the forefront of this field. Since cloning of the CF gene ...
USA Today11d
Everything to know about cystic fibrosis and what causes it
The genetic disorder cystic fibrosis is unique because it can cause both breathing and digestive problems. Some 40,000 people in the U.S. currently have it, "though this is likely an ...