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Computer simulations of the system by Joel M. Bowman of Emory University were key to understanding this behavior, and they suggest the shift from conventional hydrogen bond to something more like ...
Chemistry students the world over are familiar with covalent bonds and hydrogen bonds. Now a study has revealed a strange variety of bond that acts like a hybrid of the two. Its properties raise ...
Seeking to give patients options when covalent BTK inhibitors fail, drugmakers have been pursuing noncovalent BTK inhibitors—compounds that block BTK’s activity without forming a covalent bond ...
The sharing of electrons between atoms is called a covalent bond, which holds the atoms together as a molecule. A covalent bond happens if the attractions are strong enough in both atoms and if each ...
Covalent bonds, in which two atoms are bound together by sharing a pair of electrons, form the scaffolding that underpins the majority of organic compounds. In 1931, the Nobel Laureate Linus ...
A detailed electron distribution study of the covalent bond in silicon is discussed. The study is based on the strategy employed earlier to define the covalent bond in diamond, and estimates of the ...
However, in 1931, Linus Pauling theorized that a covalent bond could exist with atoms sharing a single electron. However, creating a new single-electron chemical bond isn't easy.
Uranium forms an unusually strong triple covalent bond with nitrile groups, confounding predictions about the bond strength of actinides compared with the remainder of the periodic table. Elements ...
For the functionalization of graphene, two approaches have been taken. They are covalent and non-covalent graphene modifications. Covalent Functionalization Approaches Covalent functionalization ...
Cytotoxic Activity of Salicylic Acid-Containing Drug Models with Ionic and Covalent Binding. ACS Medicinal Chemistry Letters, 2015; 151002131101002 DOI: 10.1021/acsmedchemlett.5b00258 ...
Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...