Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

Statewide DUI arrests decline, local law enforcement weighs in on complex causes By Rick Charmoli Cadillac News Jul 10, 2025 ...

which in turn is mediated by an elevated one-carbon unit pool and the activation of the mammalian target of rapamycin complex 1 (mTORC1) signalling pathway via glycine transporter-1. Importantly, the ...

In a routine blood test that turned extraordinary, French scientists have identified the world’s newest and rarest blood group. The sole known carrier is a woman from Guadeloupe whose blood is ...

In the world of next-generation energy, researchers are taking a leap beyond chemistry into the strange rules of quantum mechanics. A new type of battery, known as a quantum battery, is no longer just ...

Milestone marks a key advancement in the partnership with Ipsen. MONTRÉAL , July 8, 2025 /PRNewswire/ - IRIC and IRICoR today announced the start of a Phase 1 clinical trial of its small molecule ...

Then, he added the mineral iodine, which formed a complex with the dye that wouldn't break down ... All bacteria have a cell wall composed of mesh-like strands of a big molecule called peptidoglycan, ...

Single-molecule junctions (SMJs) were fabricated incorporating photochromic diarylethene units, which are covalently bonded to a bottom electrode by diazonium electro-reduction. The scanning-tunneling ...

Why is politics so insanely complicated in 2025: Trump’s chaos has spilled beyond the White House, leading to an arcane budget process and shadowy Supreme Court rulings. Good luck following any ...

A four-alarm fire broke out at South Shore Sports Complex in Hingham late-Thursday into early Friday morning. The damage to the complex is substantial which is devastating to the many local programs ...