Experts debate which patients with stage III dMMR colon cancer will benefit from the two treatment approaches.

The FDA approved an investigational new drug application for ABT-301, clearing the way for a new clinical trial in metastatic ...

Anbogen Therapeutics gains FDA approval for ABT-301, initiating a pivotal trial for metastatic colorectal cancer, targeting ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a ...

The Phase I/II trial will evaluate the safety and early efficacy of ABT-301 in combination with tislelizumab and bevacizumab ...

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a ...

New research has uncovered a novel mechanism that may help explain why some people with cancer respond remarkably well to ...

Researchers discovered that interleukin-6 (IL-6) in colorectal cancer triggers a STAT3-to-PI3K signaling switch in cancer stem cells (CSCs), enabling potent PD-L1 upregulation and immune evasion.

Chemotherapy and immunotherapy are key cancer treatments. Chemotherapy targets fast-growing cells. Immunotherapy uses the ...

Researchers have discovered new pathways that may explain differences in the way people with cancer respond to ...

Cardiff Oncology reveals promising results for onvansertib in treating KRAS- or NRAS-mutated metastatic colorectal cancer, ...

Eating more ultra-processed food (UPF) increases lung cancer risk by 41%. Risks grow fast with each daily serving, even for ...