In patients with RCC, exceptional response to immunotherapy may be related to clonal neoantigen-driven cytotoxic T-cell ...

Study: Ongoing replication stress tolerance and clonal T cell responses distinguish ... profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma (PDAC).

Pelareorep combination therapy shows continued meaningful improvement over checkpoint inhibitors alone in anal cancer patients Thomas Heineman, M.D., Ph.D., Chief Medical Officer for Oncolytics ...

Metastatic clear cell renal cell carcinoma ... patients with exceptional responses had a significantly higher total of clonal neoantigens, which are unique DNA changes present on all of the ...

Although only a small subset of patients with metastatic PDAC who have microsatellite instability ... Evaluation of tumor-infiltrating lymphocyte clonal expansion and other immunological changes in ...

2 Dr. Palapattu notes that there is likely a clonal origin of metastases: 3 Breast cancer is decades ahead of prostate cancer with regards to understanding primary treatment and collaborative risk ...

The 2-year benefit of bevacizumab in colorectal cancer may explain why survival benefits are seen in studies with two-year, ...