We demonstrate dynamic evolution of resistance to combined EGFR/BRAF/MEK inhibition in a pediatric patient with metastatic BRAF-V600E-mutant, mismatch repair-stable colon cancer. Initial resistance to ...

Clonal hematopoiesis of indeterminate potential (CHIP) is a prevalent age-associated condition involving the expansion of blood cells derived from a somatically mutated hematopoietic stem cell ...

Researchers published a new study, “ Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...