McCaffrey responds to durability questions as if he’s shaking off a tackler. “I don’t think about that,” McCaffrey said Wednesday as the 49ers wrapped up their offseason.

Since being drafted by the Carolina Panthers in 2017, McCaffrey has been one of the NFL's elite dual-threat running backs when healthy. But in 2024, some of McCaffrey's past issues with injuries ...

Christian McCaffrey and Isaac Guerendo are the only notable returning players in 2025. The rest of the depth chart is rounded out by rookie Jordan James and undrafted free agent Corey Kiner.

McCaffrey's absence wasn't the only issue ailing the 49ers, who fell short of expectations across the board, most notably with a defense that allowed 25.6 points per game. But it didn't help.

When he won AP offensive player of the year in 2023, McCaffrey led the league with 1,459 yards rushing, 339 touches, 2,023 yards from scrimmage, and 23 total touchdowns.

After struggling through multiple injuries in 2024, running back Christian McCaffrey is healthy as the 49ers complete their offseason program this week. A day after head coach Kyle Shanahan called him ...

National Football League Christian McCaffrey Hopes Longer Offseason Leads to Better Health in 2025 Published Jun. 16, 2025 10:25 p.m. ET ...

Sports 49ers' Christian McCaffrey hopes longer offseason leads to better health in 2025 June 16, 2025 / 1:14 PM PDT / AP Red & Gold Report: 49ers enter the offseason much sooner than expected ...

That is why Pro Football Network has named McCaffrey as the likeliest 49ers player to win the NFL MVP award. Here is what their analyst, Brandon Austin, had to say about the choice.

San Francisco 49ers running back Christian McCaffrey (23) catches a pass during practice at NFL football minicamp Wednesday, June 11, 2025, in Santa Clara, Calif.

SANTA CLARA, Calif. (AP) — The biggest beneficiary of an extended offseason for the San Francisco 49ers just might have been star running back Christian McCaffrey. A year after he was limited to ...

McCaffrey, who turned 29 earlier this month, said the key as he ages is finding the "middle ground" of doing the intense work to get ready for a season and making sure he doesn't wear down early.