Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...
A new study in the Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic acid-inducible gene I ...
Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver
It is a proinflammatory enzyme that metabolises 2-arachidonoylglycerol, an endocannabinoid receptor ligand, into arachidonic acid. Here, we investigated the impact of MAGL on inflammation and fibrosis ...
Plasmon Nanotechnologies, Istituto Italiano di Tecnologia, Via Morego 30, Genoa 16153, Italy Department of Biology, University of Pisa, S.S. 12 Abetone e Brennero, 4, Pisa 56127, Italy ...
In the coadministration strategy, the chemokine-expressing construct was ... of the established solid tumors [89] CCL21 + mitomycin C Breast cancer MCF-7 cells Augmentation of mitomycin C ...
1Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California.
Although C-C chemokine receptor 4 (CCR4) has been shown to mediate the recruitment ... 40 For analysis of atherosclerotic lesions in the aortic root, 5 consecutive sections (10 μm thickness), spanning ...
Tanaka and colleagues addressed the role of the C-C chemokine receptor 4 (CCR4) in early atherosclerotic plaque ... Ccr4-/- Apoe-/- mice compared to Apoe-/- mice (Supplementary Fig 5), which would be ...
New York, USA, Jan. 22, 2025 (GLOBE NEWSWIRE) -- 5-HT2 Agonist Clinical Trial Pipeline ... by enabling selective targeting of specific receptor subtypes (e.g., 5-HT2A or 5-HT2C), reducing side ...
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