Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to ...

Excitatory synapses are located in confined chemical spaces called the dendritic ... recording methods (such as total internal reflection microscopy and two-photon laser scanning microscopy ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical ...

Visualizing the precise location and motion of proteins at the synapse is possible with super-resolution fluorescence microscopy, which, unlike conventional light microscopy, is not constrained by ...

Raman microscopy ... it can provide chemical information about specific molecules—such as proteins—that take part in the body's processes. However, the Raman light that comes from biological ...

SynPull combines single-molecule pull-down of synaptosomes with direct stochastic optical reconstruction microscopy ... synapses from human brain samples with Aβ pathology. The method can be adapted ...