The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

And the orange couch, a key set piece on the show, is re-created here. And for good reason. “It’s central to Victor so why don’t we call it the Central Perk?” Rizzo-Budd said.

Reporters found nearly 50 cases since 2013 in which vulnerable group home residents died amid alarming questions about their care and supervision.

Fans can even pose with Ross’s “pivot!” sofa, Chandler and Joey’s foosball table, and on the infamous orange Central Perk couch, where they can try a seasonal menu of beverages and pastries.

OTTO, Mo. — An Otto resident with a huge love of “Friends” recently opened a resale shop named after the coffee shop commonly frequented by the characters of the hit show. Kim Sauer opened ...

The ultimate Friends fan auction is here! From Rachel's gray sweater to Chandler's iconic green sweater, and even a Central Perk couch reproduction, you can own a piece of television history.

The velvet couch that serves as the friends’ coffee-shop perch went for $29,250, 10 to 15 times more than the initial estimate of $2,000 to $3,000. Likewise a reproduction of the Central Perk ...

A sweater worn by the late Matthew Perry and a reproduction of the iconic Central Perk couch have sold for thousands at an auction celebrating Friends‘ 30th anniversary. Friends: The One With ...