Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia.The ...

Single-cell analysis of over 120,000 cells reveals how mitochondrial DNA mutations accumulate with age and may affect ageing and neurodegeneration.New ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

A new study published in Nature reveals how olfactory sensory neurons (OSNs) achieve extraordinary precision in selecting ...

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...

In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

A study introduces a CRISPR model that predicts gRNA activity more accurately using chemically synthesized gRNAs. The model ...

Boys who gain excess weight during puberty may cause gene changes in future children, raising their risk for obesity and poor ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

Analysis of breast cancer screening results in urban areas of Henan Province. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This abstract does not include a full text component ...

The flow from sequence information to experimentation is ... and do not have to contain only a single (or small number of) DNA species. For example, eleven different exons are analysed in parallel ...