Tracking every blood cell back to its original stem cell requires genetically modifying DNA. In humans ... that researchers can "scan" or read to chart each cell's position in the family tree.

Cell-free gene synthesis eliminates the need for bacterial cloning, which has been the conventional method for high-quality gene-length DNA production. Cloning involves lengthy culturing steps, is ...

Each cell in a plant, animal, or person contains millions, or even billions, of DNA base pairs—molecules ... In order to chart human migration patterns, investigate animal domestication, and ...

Zooming in on individual cells The body has various mechanisms to repair DNA, but the process can differ from cell to cell. This makes it important to study DNA repair in individual cells.

"Mitochondrial DNA is essential for cell function," Dr Hahn said. "But as we age it mutates, contributing to diseases like dementia, cancer and diabetes. "Our team identified 2 enzymes that ...

The team then used a technique called ADPr-Seq to map where these tags appeared across the genome, alongside live-cell imaging and RNA sequencing to track changes in DNA replication, cell division ...

They also tend to use heat to separate strands, heating the DNA to more than 150°F, a temperature a cell would never naturally reach. By contrast, in a living cell DNA lives in a very crowded ...

As a graduate student in 2000, he spent six months trying to build a cell that could periodically alter a tiny bit of its own DNA. After six months of failure, he abandoned the project.

"This work is a milestone in the application of DNA nanotechnology to regulate cell behavior," Liu says. The team works with giant unilamellar vesicles (GUVs), which are simple, cell-sized ...